Good morning, Daniel. Tuesday, March 03, 2026
Although I’m optimistic that AI will design better drug candidates, this alone cannot ensure “therapeutic abundance,” for a few reasons. First, because the history of drug development shows that even when strong preclinical models exist for a condition, like osteoporosis, the high costs needed to...
Many of you got upset when I mentioned the possibility that parents use smart phone software to control the social media usage of their kids. There was an outcry about how badly those systems work (is that endogenous?). But that is missing the point. If you wish to limit social media usage, man...
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...Ruxandra Teslo asks a good question: I have a curiosity: why is it the case that it is easier to get MAID in Canada than it is to access experimental treatments which carry a higher risk? In the past, I used to think ppl do not like “deaths caused by the medical system”, but for [R...
1. “It’s a win for fairly orthodox economic thought.” Yessirree. 2. Maybe the public does not hate AI? 3. Cees Nooteboom, RIP. 4. “Neanderthal men in Neanderthal societies may have had a strong attraction to hybrid women — that is, to women with a modern human parent or g...
On the war, Matt Yglesias has a good take. On AI and the military, Ross Douthat has a good take (NYT). If you wish to sample an “outside the box” opinion, here is Eliezer.
The post Some opi...
A landmark law that limits children under the age of 16 to one hour per day on social media apps has been blocked by a US court, in a blow to child safety campaigners seeking to limit exposure to sites such as Instagram and YouTube. In an opinion released on Friday, a federal judge in […]
I promised you I would be tracking this issue, and so here is a major development. From the QJE by Adrien Bilal and Diego R Känzig:: This paper estimates that the macroeconomic damages from climate change are an order of magnitude larger than previously thought. Exploiting natural global tempera...
Yes I will be doing a Conversation with her. She is the author of a forthcoming book on Weimar, namely Weimar: Life on the Edge of Catastrophe. Note that much of the book considers the city of Weimar, mostly in Nazi times, and not just the Weimar era. She also has published Beyond the Wall: [&...
1. “Model this.” 2. UAE to cover expenses for affected travelers. And “emergency visas” are issued on the spot. 3. Abbas Amanat, Iran: A Modern History is for me (by far) the best general history of the country. I like the cover too. 4. From two weeks ago: “Perhaps...
Some observations and comments on Trump and Israel’s war on Iran: 1. Tehran is not looking for a ceasefire and has rejected outreach from Trump. The reason is that they believe they committed a mistake by agreeing to the ceasefire in June – it only enabled the US and Israel to restock...
Numerous nations in the Middle East are being pulled into the current conflict and have received missile attacks from Iran. I believe the proper Bayesian update is that Brazil is underrated. The country has plenty of water, and lots of capacity to grow its own food. It is an agricultural powerh...
My latest paper, Chaos and Misallocation under Price Controls, (with Brian Albrecht and Mark Whitmeyer) has a new take on price controls: Price controls kill the incentive for arbitrage. We prove a Chaos Theorem: under a binding price ceiling, suppliers are indifferent across destinations, so arb...
From my new Free Press column, I see these as the most important facts: Congress has not passed explicit regulation of AI foundation models, and an executive order from President Trump limited regulation at the state level. But do not think that laissez-faire reigns. In addition to existing (larg...
1. Claims about drones. 2. Just say no to the monopsony model. 3. Your dose of John Cochrane. 4. More on the recent climate change estimate. It seems the paper should not have been published? 5. “During their lives, centenarians rarely get sick.“
The post
Article URL: https://www.apple.com/newsroom/2026/03/apple-introduces-the-new-ipad-air-powered-by-m4/ Comments URL: https://news.ycom...
Article URL: https://schipper.ai/posts/parallel-coding-agents/
Comments URL: https://news.ycombinator.com/item?id=47218318
Points: 121
# Comments: 90
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Hi HN! My name is Rohan and, together with Paul, I’m the co-founder of OctaPulse (https://www.tryoctapulse.com/). We’re building a robotics layer for seafood production, starting with automated fish inspection. We are currently deployed at our first pro...
Article URL: https://www.ycombinator.com/companies/reflex/jobs
Comments URL: https://news.ycombinator.com/item?id=47220666
Points: 0
# Comments: 0
...Govbase tracks every bill, executive order, and federal regulation from official sources (Congress.gov, Federal Register, White House). An AI pipeline breaks each one down into plain-language summaries and shows who it impacts by demographic group.
It also ties each policy directly to bias-rate...
Article URL: https://starlightconvenience.net/#that-shape-had-none
Comments URL: https://news.ycombinator.com/item?id=47222226
Points: 80
# Comments...
A filter list for uBO that blurs all video and non-follower content from Instagram. Works on mobile with uBO Lite.
related: https://news.ycombinator.com/item?id=47016443
Comments URL:
Article URL: https://www.cbc.ca/news/canada/british-columbia/b-c-adopting-year-round-daylight-time-9.7111657 Comments URL: h...
A little weekend project, made so I can pause/play/rewind directly on the piano, when learning a song by ear.
Comments URL: https://news.ycombinator.com/item?id=47223863
Points: 39
# Comments: 15
...Article URL: https://take.surf/2026/03/01/welcome-back-to-macintosh
Comments URL: https://news.ycombinator.com/item?id=47224118
Points: 245
# Comme...
I built a voice agent from scratch that averages ~400ms end-to-end latency (phone stop → first syllable). That’s with full STT → LLM → TTS in the loop, clean barge-ins, and no precomputed responses.
What moved the needle:
Voice is a turn-taking problem, not a transcription problem. VAD alone ...
Article URL: https://blog.sturdystatistics.com/posts/type_hint/
Comments URL: https://news.ycombinator.com/item?id=47224832
Points: 40
# Comments: 2